The victim, who's in his thirties, is in hospital with non-life threatening injuries.
Police and ambulance crews were called to Blackbird Leys Park, off Pegasus Road, just before 10pm yesterday.
The stabbing victim was taken to hospital, where he remains this afternoon.
The offenders are all described as black males, and were all wearing face coverings.
Thames Valley Police is reassuring residents that none of the recent knife-related offences in Oxford are linked and they are all isolated incidents.
Investigating officer Detective Inspector James Mather, of Oxford CID, said: “Although I understand this incident will cause concern in the local community, at this stage, we do not believe this to have been a random attack.
“There is an increased police presence in the area while our investigation continues, but we do not believe there is a wider risk to the local community.”
Witnesses are being urged to contact TVP either online or via 101, quoting reference number 43210472676.
Superintendent Bruce Riddell, Local Policing Area commander for Oxford, added: “I would like to reassure the public that none of the recent knife-related incidents in the city are linked, and to that extent, they are all isolated occurrences.
“However, it’s entirely understandable the concern such incidents cause, and we are committed to reducing knife crime and the threat of knife-related incidents in Oxford.
“In additional to our operational response, we continue to work closely with the Violence Reduction Unit and other partners, including Oxford City Council, to implement early intervention programmes and strive to prevent incidents such as these from taking place.
“Our communities play a crucial role too, and you can report any information to Thames Valley Police if you know of any individuals who are carrying weapons or are at risk of doing so."
Police have stepped up patrols in the last two weeks, including high visibility neighbourhood patrols with both police officers and PCSOs.
Superintendent Riddell said that these 'will continue in the coming days and weeks.'
He added: “Thankfully, the incident in Greater Leys has not led to life threatening or life changing injuries.
“Regarding the recent previous incidents in Barton and Botley, we have made arrests in both of these, and in the case of the Barton incident, a man has been charged and remanded.
“We remain absolutely resolute in our determination to removing knives and knife crime in our communities and will continue to work with all of our partners in doing so.”
We're appealing for witnesses after a man was stabbed in Oxford, last night.— TVP Oxford (@TVP_Oxford) October 20, 2021
It happened between 9.30pm and 9.50pm in Blackbird Leys Park, off Pegasus Road.
The victim then walked through Gillians Park after the incident.
Info? 📞 101 quoting 43210472676https://t.co/zwsYymCnRK pic.twitter.com/01bW1IOwxP